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The FDA-approved labeling for tapentadol includes boxed warnings for addiction, abuse, and misuse; life-threatening respiratory depression; accidental ingestion; neonatal opioid withdrawal syndrome; and risks from concomitant use with benzodiazepines or other CNS depressants . Cases of serotonin syndrome, a potentially life-threatening condition, have been reported during concurrent use of tapentadol with serotonergic drugs, and symptoms may include mental-status changes, autonomic instability, neuromuscular aberrations, and gastrointestinal symptoms . Adrenal insufficiency and severe hypotension have also been reported with opioid use . When you buy Tapentadol online from RxMedsKart, our U.S.
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