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The drug was first synthesized in 1960 by Leo Sternbach at Hoffmann-La Roche, a pharmaceutical company known for pioneering benzodiazepines. It was introduced to the market in the United States in 1975 under the brand name Klonopin. Since then, it has become one of the most commonly prescribed benzodiazepines due to its efficacy and relatively long half-life compared to other drugs in its class.Clonazepam comes in both brand-name and generic forms and is available in various dosage strengths, including tablets, orally disintegrating tablets, and an oral solution. The dosage prescribed depends on the condition being treated and individual patient factors, such as age, weight, and medical history.
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